Cureus. 2025 Apr 11;17(4):e82109. doi: 10.7759/cureus.82109. eCollection 2025 Apr.
ABSTRACT
A 29-year-old postpartum woman with no prior Noonan syndrome diagnosis was admitted for recurrent chest pain, dyspnea, and palpitations. She had two adverse pregnancy outcomes, including a neonatal death due to perinatal asphyxia. Physical examination revealed characteristic facial features, and echocardiography confirmed biventricular failure, hypertrophic cardiomyopathy, and a 2.5 cm intracavitary thrombus in the left ventricle. She was treated with heart failure management, anticoagulation, and diuretics before being referred to a specialized cardiology center. This case highlights the challenges in diagnosing and managing cardiovascular complications in suspected Noonan syndrome.
PMID:40357110 | PMC:PMC12066870 | DOI:10.7759/cureus.82109
