Neutralizing Antibody Immune Correlates for a Recombinant Protein Vaccine in the COVAIL Trial
Neutralizing Antibody Immune Correlates for a Recombinant Protein Vaccine in the COVAIL Trial

Neutralizing Antibody Immune Correlates for a Recombinant Protein Vaccine in the COVAIL Trial

Clin Infect Dis. 2024 Sep 26:ciae465. doi: 10.1093/cid/ciae465. Online ahead of print.

ABSTRACT

For COVAIL recipients of a COVID-19 Sanofi booster vaccine, neutralizing antibody titers were assessed as a correlate of risk (CoR) of COVID-19. Peak and exposure-proximal titers were inverse CoRs with covariate-adjusted hazard ratios (95% confidence intervals) 0.30 (0.11, 0.78) and 0.25 (0.07, 0.85) per 10-fold increase in weighted average titer.

PMID:39325506 | DOI:10.1093/cid/ciae465