Neonatal Outcomes in Transposition of the Great Arteries by Mode and Timing of Delivery
Neonatal Outcomes in Transposition of the Great Arteries by Mode and Timing of Delivery

Neonatal Outcomes in Transposition of the Great Arteries by Mode and Timing of Delivery

Am J Perinatol. 2025 Jul 30. doi: 10.1055/a-2672-2713. Online ahead of print.

ABSTRACT

OBJECTIVE: We aimed to assess neonatal outcomes by mode of delivery and to evaluate the value of achieving daytime delivery among neonates undergoing a planned induction of labor (IOL).

METHOD: This was a retrospective study of pregnancies with prenatally diagnosed d-TGA with an IVS receiving care at a single tertiary care referral center from 2020-23. Inclusion required prenatal diagnosis of d-TGA with an IVS and surgical care at the referral center. The primary outcome was a composite of neonatal outcomes. Pearson chi-square or Fisher’s exact test were performed as appropriate.

RESULTS: We identified 90 cases of prenatally diagnosed d-TGA, of which 68 (76%) underwent timed IOL and 46 (68%) achieved vaginal delivery. The primary outcome occurred in 16 neonates (89%) who delivered by cesarean and 47 neonates (78%) who underwent a planned timed IOL (p=0.26). Among individuals undergoing IOL, the primary outcome occurred in 29 neonates (73%) who delivered during the daytime and 18 (90%) who delivered after-hours (p=0.19).

CONCLUSION: We found that in cases of prenatally diagnosed d-TGA with an IVS , IOL is feasible. Neonates with d-TGA with an IVS had similar surgical outcomes when induced and delivered at this single tertiary care center, regardless of delivery time.

PMID:40738137 | DOI:10.1055/a-2672-2713