Cureus. 2024 Sep 27;16(9):e70316. doi: 10.7759/cureus.70316. eCollection 2024 Sep.
ABSTRACT
Background Chronic hypertension (CHTN) has been associated with significant maternal and neonatal complications. The goal of this research study is to assess outcomes and management strategies among pregnant women living with CHTN. Methods From December 2019 to December 2020, 50 pregnant women diagnosed with CHTN before or at 20 weeks gestation at Cure International Hospital, Kabul, Afghanistan, underwent retrospective analysis using data obtained from patient records, such as demographic details, clinical history notes, laboratory test findings, imaging results, management protocols, and maternal and neonatal outcomes. Results Of the 50 patients, 17 (34%) developed superimposed preeclampsia. Maternal complications included superimposed preeclampsia in 17 (34%), placental abruption in 14 (28%), gestational diabetes in 15 (30%), and acute kidney injury in one (2%). Neonatal complications included preterm birth (12; 24%), low birth weight (12; 24%), small for gestational age (10; 20%), and perinatal mortality (5; 10%). Management strategies revealed that 38 (75%) patients received labetalol, while 12 (25%) were treated with methyldopa. Conclusions CHTN during gestation can result in significant maternal and neonatal complications, and adherence to management guidelines is critical to improve outcomes. More studies are necessary to develop optimal treatment protocols and preventive measures.
PMID:39469348 | PMC:PMC11513204 | DOI:10.7759/cureus.70316
