Intraosseous myofibroma mimicking an odontogenic lesion: case report, literature review, and differential diagnosis
Intraosseous myofibroma mimicking an odontogenic lesion: case report, literature review, and differential diagnosis

Intraosseous myofibroma mimicking an odontogenic lesion: case report, literature review, and differential diagnosis

World J Surg Oncol. 2024 Sep 12;22(1):246. doi: 10.1186/s12957-024-03520-4.

ABSTRACT

BACKGROUND: Intraosseous myofibroma of the jaw is a rare neoplasm of mesenchymal origin with limited comprehensive understanding. It typically affects patients in the first two decades of life with a male predilection.

CASE PRESENTATION: This study presents a rare case of myofibroma mimicking an odontogenic lesion in a 2-year-old boy. The patient presented with an incidental finding of a painless swelling of the right mandibular ramus of unknown etiology. Imaging analysis revealed a solid, expansile lesion adjacent to the germinal zone of the right mandibular first molar. Histopathologic analysis and immunohistochemistry after incisional biopsy suggested a possible central odontogenic fibroma, and the patient underwent total enucleation, leading to the final diagnosis of intraosseous myofibroma. Follow-up examinations showed no evidence of recurrence.

CONCLUSIONS: This report contributes to the understanding of myofibroma in pediatric patients and underscores the critical role of meticulous histopathologic examination for effective surgical planning and optimal patient outcomes.

PMID:39267062 | DOI:10.1186/s12957-024-03520-4