J Urol. 2025 Jun 18:101097JU0000000000004645. doi: 10.1097/JU.0000000000004645. Online ahead of print.
ABSTRACT
PURPOSE: Pediatric urolithiasis is a common clinical condition that can cause kidney damage and long-term health complications. This study aims to assess the trends in incidence, prevalence, and disability-adjusted life years of pediatric urolithiasis from 1990 to 2021, and to predict the burden of the disease in 2040.
MATERIALS AND METHODS: Detailed information on Pediatric urolithiasis from 1990 to 2021 was collected from the Global Burden of Disease Database 2021. Based on Global Burden of Disease data, a systematic approach was used to analyze the burden and trends in the incidence, prevalence, and disability-adjusted life years of pediatric urolithiasis from 1990 to 2021, and to predict the disease burden in 2040.
RESULTS: In 2021, there were 1,560,000 new cases, representing a 15% increase compared to 1990, with 920,000 cases in boys (58%) and 640,000 cases in girls (41%). Prevalence rose by 15%, while disability-adjusted life years decreased by 43% compared to 1990. However, from 2015 to 2021, both incidence and prevalence of pediatric urolithiasis significantly increased. Regions with lower Socio-Demographic Index exhibited higher incidence, prevalence, and disability-adjusted life years, exacerbating disparities in disease burden. By 2040, incidence is expected to exceed 1.53 million.
CONCLUSIONS: Global incidence and prevalence are expected to continue rising. Although disability-adjusted life years have decreased, health inequities remain prominent, particularly in low Socio-Demographic Index regions. To address the growing burden of pediatric urolithiasis, focusing on low Socio-Demographic Index areas is crucial, prioritizing access to prevention and treatment resources to improve global child urological health.
PMID:40532191 | DOI:10.1097/JU.0000000000004645
