iScience. 2026 Mar 10;29(4):115296. doi: 10.1016/j.isci.2026.115296. eCollection 2026 Apr 17.
ABSTRACT
This study provides a comprehensive assessment of the global burden of childhood epilepsy attributable to neonatal disorders, using data from the Global Burden of Disease Study 2021. From 1990 to 2021, the age-standardized prevalence rate and number of years lived with disability increased globally, with higher burdens observed among boys and in regions with lower Sociodemographic Index levels. Preterm birth was identified as the most significant neonatal cause of childhood epilepsy. These findings depict the burden of epilepsy attributable to neonatal disorders in children and underscore the need for targeted perinatal care strategies, particularly in low-resource settings, to reduce the long-term neurological sequelae in children worldwide.
PMID:41940342 | PMC:PMC13049413 | DOI:10.1016/j.isci.2026.115296
