Bull Exp Biol Med. 2024 Jul 4. doi: 10.1007/s10517-024-06148-2. Online ahead of print.
ABSTRACT
Experimental model of resection craniotomy with subsequent reconstruction of the defect with a polymer implant enables comprehensive assessment of functional and ultrastructural changes during replacement of the damaged tissue. Reconstruction of a skull defect was accompanied by transient motor disturbance in the acute period and did not cause functional disorders and neurological deficits in a delayed period. Histological examination of osteal and brain tissue revealed no pathological reactions that could be associated with the response to the chemical components of the implant.
PMID:38963597 | DOI:10.1007/s10517-024-06148-2
