Pak J Med Sci. 2025 Jan;41(1):219-224. doi: 10.12669/pjms.41.1.9777.
ABSTRACT
OBJECTIVE: To determine the diagnostic accuracy and procedure safety of ultrasound-guided core needle biopsy of extra cranial solid masses in the pediatric population.
METHOD: A cross-sectional survey was conducted by the Department of Pediatric Hematology /Oncology and Radiology at Indus Hospital and Health Network Karachi from August 2022 to April 2023. A total of 118 pediatric patients, from age one month to 18 years, with extra cranial solid masses were studied. Data was analyzed using SPSS version 24.
RESULTS: The median age of study participants was six years with IQR = 7.2 years. Among all study participants 62.7% (n=74) were male while 37.3% (44) were female. Out of all biopsies 94.07% (n=111) were conclusive and provided an accurate diagnosis of the tumor while only 5.63% (n=07) biopsies remained inconclusive. No serious post-procedure complication was reported. Pain on the site of biopsy was the most post-procedure complain reported by 34.7% (n=41) of all the study participants. Forty-two percent of the study participants never reported any post-procedure complaints after ultrasound-guided biopsy. The diagnostic accuracy was significantly higher for malignant lesions as compared to non-malignant lesions.
CONCLUSION: Ultrasound-guided percutaneous core needle biopsy had high diagnostic accuracy and a good safety profile among children with extra cranial solid masses in private tertiary care hospital in Karachi Pakistan.
PMID:39867795 | PMC:PMC11755276 | DOI:10.12669/pjms.41.1.9777
