Appl Neuropsychol Child. 2025 Mar 15:1-8. doi: 10.1080/21622965.2025.2479857. Online ahead of print.
ABSTRACT
BACKGROUND: Brain tumors are the most common type of pediatric cancer, significantly impacting children’s health-related quality of life (HRQoL). This study aimed to adapt the PedsQL™-BTM to Turkish culture and evaluate its psychometric properties, including reliability, validity, and cross-cultural consistency.
METHOD: A total of 108 children with brain tumors (mean age: 9.1 ± 4.99 years) and 120 parents participated in the study. The translation process included forward-backward translation, reconciliation, cognitive debriefing, and pilot testing. Internal consistency (Cronbach’s alpha), test-retest reliability (ICC), exploratory and confirmatory factor analysis were conducted to evaluate the psychometric properties. Correlations between the PedsQL™-BTM and the Generic Core Scales were examined for criterion validity.
RESULTS: Cronbach’s alpha ranged from 0.83 to 0.97, indicating excellent internal consistency. Test-retest reliability was robust, with ICC values exceeding 0.80 for most subscales. EFA explained 84.2% of the variance in parent reports and 80.4% in child reports, while CFA confirmed the six-factor structure (child-reported outcomes: RMSEA = 0.069, 90% CI: 0.061-0.076; TLI = 0.862; NFI = 0.92; χ2 (147) = 1875, p < 0.001; and parent-reported outcomes: RMSEA = 0.063, 90% CI: 0.059-0.069; TLI = 0.858; NFI = 0.93; χ2 (153) = 1912, p < 0.001). Correlations between the BTM subscales and Generic Core Scales demonstrated strong criterion validity (e.g. Cognitive Problems correlated with School Functioning: r = 0.831, p < 0.05).
CONCLUSIONS: The Turkish PedsQL™-BTM is a reliable and valid tool for assessing HRQoL in children with brain tumors.
PMID:40088496 | DOI:10.1080/21622965.2025.2479857
