Concomitant Rifampicin-Sensitive Pulmonary Tuberculosis With Pre-extremely Drug-Resistant Neuro-Tuberculosis in Child With Steroid-Resistant Nephrotic Syndrome
Concomitant Rifampicin-Sensitive Pulmonary Tuberculosis With Pre-extremely Drug-Resistant Neuro-Tuberculosis in Child With Steroid-Resistant Nephrotic Syndrome

Concomitant Rifampicin-Sensitive Pulmonary Tuberculosis With Pre-extremely Drug-Resistant Neuro-Tuberculosis in Child With Steroid-Resistant Nephrotic Syndrome

Pediatr Infect Dis J. 2024 Sep 18. doi: 10.1097/INF.0000000000004555. Online ahead of print.

ABSTRACT

Mixed tuberculosis occurs with multiple clonally distinct mycobacterium tuberculosis strains in an individual. We present a 12-year-old girl with steroid-resistant nephrotic syndrome and drug-sensitive pulmonary tuberculosis (Xpert MTB/Rif) and preextensively drug-resistant tuberculosis neuro-tuberculosis (Line Probe Assay). Mixed tuberculosis involving drug-susceptible and drug-resistant strains can hinder treatment. This case highlights the challenges in diagnosing mixed tuberculosis to ensure effective management.

PMID:39292926 | DOI:10.1097/INF.0000000000004555