Paediatrics
Paediatrics

A Multisite Implementation of the Comfort Ability Program Telehealth Intervention for Pediatric Chronic Pain: Insights from Patients, Caregivers, and Providers

Clin J Pain. 2025 Nov 13. doi: 10.1097/AJP.0000000000001330. Online ahead of print. ABSTRACT OBJECTIVE: The primary aim of this multisite study was to evaluate feasibility …

Clinical phenotype and genetic analysis of a child with Progressive familial intrahepatic cholestasis type 8 due to compound heterozygous variants of KIF12 gene

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2025 Sep 10;42(9):1132-1140. doi: 10.3760/cma.j.cn511374-20241203-00632. ABSTRACT OBJECTIVE: To explore the clinical manifestation and genotype of a child …

Clinical characteristics and genetic study of a child with Spastic paraplegia 52 due to variant of AP4S1 gene and a literature review

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2025 Sep 10;42(9):1106-1113. doi: 10.3760/cma.j.cn511374-20241031-00572. ABSTRACT OBJECTIVE: To explore the clinical phenotype and genetic characteristics of a …

A randomised controlled trial comparing epinephrine and dexamethasone to placebo in the treatment of infants with bronchiolitis (BIPED study): a statistical analysis plan

Trials. 2025 Nov 12;26(1):496. doi: 10.1186/s13063-025-09125-w. ABSTRACT BACKGROUND: Bronchiolitis is a common lung infection that affects infants and young children. While most children can be …

Efficacy of non-pharmacological interventions for childhood asthma: a systematic review and network meta-analysis

BMC Pediatr. 2025 Nov 12;25(1):927. doi: 10.1186/s12887-025-06115-4. ABSTRACT BACKGROUND: Childhood asthma is a prevalent chronic respiratory disease. While inhaled corticosteroids and β-agonists remain cornerstone treatments, …

Pravastatin for the prevention of recurrent hypertensive disorders of pregnancy: study protocol for a randomized, open-label, parallel-group, three-arm trial

Trials. 2025 Nov 12;26(1):499. doi: 10.1186/s13063-025-09136-7. ABSTRACT BACKGROUND: Hypertensive disorders of pregnancy lead to a critically ill maternal/fetal state due to maternal organ failure and …

Study protocol for a multicenter, multinational prospective randomized controlled trial comparing outcomes in subjects with Gram-negative bacteremia who have blood culture evaluation using Fast Antibiotic Susceptibility Testing vs. standard of care testing: the FAST trial

Trials. 2025 Nov 12;26(1):500. doi: 10.1186/s13063-025-09228-4. ABSTRACT BACKGROUND: Novel, rapid blood culture diagnostics can provide faster antibiotic susceptibility results (AST) compared to standard methods but …

Barriers and facilitators to exclusive breastfeeding among formally employed mothers in urban Indonesia

BMC Public Health. 2025 Nov 12;25(1):3925. doi: 10.1186/s12889-025-25214-6. ABSTRACT BACKGROUND: Despite global and national recommendations, exclusive breastfeeding (EBF) remains suboptimal among formally employed mothers in …