Paediatrics
Paediatrics

What have we learned from long-term studies in juvenile idiopathic arthritis? – Prediction, classification, transition

Pediatr Rheumatol Online J. 2025 Feb 19;23(1):18. doi: 10.1186/s12969-025-01070-x. ABSTRACT BACKGROUND: Research and management of juvenile idiopathic arthritis (JIA) are challenging due to its heterogeneous …

Safety and effectiveness of intravenous abatacept for polyarticular-course juvenile idiopathic arthritis: An all-case postmarketing surveillance study

Pediatr Rheumatol Online J. 2025 Feb 19;23(1):19. doi: 10.1186/s12969-025-01069-4. ABSTRACT BACKGROUND: In 2018, intravenous abatacept was approved for the treatment of refractory polyarticular-course juvenile idiopathic …

AAV1.NT3 gene therapy mitigates the severity of autoimmune encephalomyelitis in the mouse model for multiple sclerosis

Gene Ther. 2025 Feb 19. doi: 10.1038/s41434-025-00518-9. Online ahead of print. ABSTRACT Multiple sclerosis (MS) is an immune-mediated chronic inflammatory and neurodegenerative disease of the …