Paediatrics
Paediatrics

The long reach of puberty: mechanisms underlying sex-dependent links between pubertal timing and adult internalizing symptoms

Psychol Med. 2025 Apr 14;55:e115. doi: 10.1017/S0033291725000820. ABSTRACT BACKGROUND: Pubertal development variations have consequences for adolescent internalizing problems, which likely continue into adulthood. Key questions …

The RBM39 degrader indisulam inhibits acute megakaryoblastic leukemia by altering the alternative splicing of ZMYND8

Cell Biosci. 2025 Apr 13;15(1):46. doi: 10.1186/s13578-025-01380-3. ABSTRACT BACKGROUND: Acute megakaryoblastic leukemia (AMKL) is a rare hematological malignancy in adults but children. Alternative splicing (AS) …

Prevalence and comorbidity of attention deficit hyperactivity disorder in Chinese school-attending students aged 6-16: a national survey

Ann Gen Psychiatry. 2025 Apr 13;24(1):23. doi: 10.1186/s12991-025-00558-w. ABSTRACT BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder. Despite its significance, no large-scale …