Paediatrics
Paediatrics

Outcomes of PLAT-02 and PLAT-03: Evaluating CD19 CAR T-Cell Therapy and CD19-expressing T-APC Support in Pediatric B-ALL

Blood. 2025 Apr 15:blood.2025028359. doi: 10.1182/blood.2025028359. Online ahead of print. ABSTRACT This study reports outcomes of PLAT-02, a phase 2 trial of SCRI-CAR19, a second-generation …

Eco-anxiety and Climate Anxiety: Bellwethers of the Climate Crisis’s Mental Health Impact on Children and Adolescents

J Dev Behav Pediatr. 2025 Mar-Apr 01;46(2):e223-e226. doi: 10.1097/DBP.0000000000001357. Epub 2025 Feb 10. ABSTRACT OBJECTIVE: To highlight the need for more research about climate change’s …

Effects of sertraline on depressive symptoms, serum brain-derived neurotrophic factor (BDNF), 5-HT, and inflammatory cytokine expression in pediatric depression patients

Exp Clin Psychopharmacol. 2025 Apr 14. doi: 10.1037/pha0000768. Online ahead of print. ABSTRACT This study investigated the therapeutic effects of sertraline in pediatric patients diagnosed …

Clinical Spectrum and Molecular Characteristics of Inherited Ocular Diseases in a Cohort of Pediatric Patients With Infantile Nystagmus Syndrome

Invest Ophthalmol Vis Sci. 2025 Apr 1;66(4):39. doi: 10.1167/iovs.66.4.39. ABSTRACT PURPOSE: Infantile nystagmus syndrome (INS), the most prevalent form of nystagmus in children, often indicates …

Fetal Growth Restriction Is Associated With Altered Optic Nerve Head Morphology in Term-Born Children and Adolescents

Invest Ophthalmol Vis Sci. 2025 Apr 1;66(4):35. doi: 10.1167/iovs.66.4.35. ABSTRACT PURPOSE: Restricted fetal growth is associated with impaired neurodevelopment in childhood. We examined the effects …