Paediatrics
Paediatrics

Multi-Targeted Kinase Inhibitor Therapy in Pediatric Bone and Soft Tissue Sarcoma Patients-A Single Centre Experience

Cancer Med. 2025 May;14(9):e70951. doi: 10.1002/cam4.70951. ABSTRACT BACKGROUND: Patients with relapsed or refractory soft tissue and bone sarcomas have dismal outcomes. Multi-targeted kinase inhibitors (mTKI) …

Safety of Single Preoperative Dose of Enoxaparin for Hepatectomy: A Study in a Country With Low Venous Thromboembolism Incidence

ANZ J Surg. 2025 May 9. doi: 10.1111/ans.70168. Online ahead of print. ABSTRACT BACKGROUND: Postoperative venous thromboembolism (VTE) prophylaxis for hepatectomy is debated in low-VTE …

Disrupted Cortico-Striato-Thalamo-Cortical Circuitry and Sleep Disturbances in Obsessive-Compulsive Spectrum, Chronic Tic, and Attention-Deficit/Hyperactivity Disorders

Harv Rev Psychiatry. 2025 May-Jun 01;33(3):114-126. doi: 10.1097/HRP.0000000000000429. ABSTRACT The bidirectional relationship between sleep and obsessive-compulsive spectrum disorders (OCSDs), chronic tic disorders (CTDs), and attention-deficit/hyperactivity …

Continuous Application of Closed-Loop FiO2-Control in Extremely Preterm Infants: A Matched Cohort Single-Center Study

Pediatr Pulmonol. 2025 May;60(5):e71122. doi: 10.1002/ppul.71122. ABSTRACT INTRODUCTION: Automated or closed-loop FiO2-control (FiO2-c) has been developed to maintain oxygen saturation (SpO2) within a target range …

The alterations of molecular repertoire of the RANKL-induced osteoclastogenesis in the M1 macrophage-derived inflammatory milieu

Sci Rep. 2025 May 8;15(1):16137. doi: 10.1038/s41598-025-99772-5. ABSTRACT Inflammation have been linked to bone diseases such as osteoporosis or bone destruction. However, whether M1 inflammatory …

Assessment of growth status and nutritional management of prematurely born infants after hospital discharge: A position paper of the ESPGHAN Nutrition Committee

J Pediatr Gastroenterol Nutr. 2025 May 8. doi: 10.1002/jpn3.70054. Online ahead of print. ABSTRACT OBJECTIVES: The aim of the manuscript is to provide evidence-based or …