Paediatrics
Paediatrics

Associations of circulating omentin-1 levels and long noncoding RNA MALAT1 expression with coronary heart disease in patients with type 2 diabetes mellitus

Sci Rep. 2025 May 11;15(1):16376. doi: 10.1038/s41598-025-01153-5. ABSTRACT Coronary heart disease (CHD) is a severe diabetic vascular complication and the main cause of mortality among …

Awareness and knowledge of pediatricians regarding genetic testing for Fragile X syndrome in Japan: A National Survey of Pediatricians Managing Developmental Delay/Intellectual disability

Brain Dev. 2025 May 10;47(4):104367. doi: 10.1016/j.braindev.2025.104367. Online ahead of print. ABSTRACT BACKGROUND: Fragile X syndrome (FXS) commonly cause developmental delay, intellectual disability, and autism …

Bilayer Electrospun Polyurethane Membrane With Tunable Elastomeric Properties for the Treatment of Congenital Diaphragmatic Hernia

J Biomed Mater Res A. 2025 May;113(5):e37926. doi: 10.1002/jbm.a.37926. ABSTRACT Congenital diaphragmatic hernia is a rare condition characterized by the development of a defect in …

Targeting neutrophil extracellular traps: SERPINE1 and THBS1 as non-invasive biomarkers for early detection of liver fibrosis in metabolic dysfunction-associated Steatotic liver disease

Int Immunopharmacol. 2025 May 10;158:114828. doi: 10.1016/j.intimp.2025.114828. Online ahead of print. ABSTRACT Metabolic dysfunction – Associated Steatotic Liver Disease (MASLD), formerly known as non-alcoholic fatty …

Temporally discordant chromatin accessibility and DNA demethylation define short- and long-term enhancer regulation during cell fate specification

Cell Rep. 2025 May 9;44(5):115680. doi: 10.1016/j.celrep.2025.115680. Online ahead of print. ABSTRACT Chromatin and DNA modifications mediate the transcriptional activity of lineage-specifying enhancers, but recent …

Comparative efficacy of epoetin alfa vs. darbepoetin in children with chronic kidney disease: a systematic review, meta-analysis and cost-effectiveness analysis

J Nephrol. 2025 May 11. doi: 10.1007/s40620-025-02303-8. Online ahead of print. ABSTRACT BACKGROUND: Recombinant human erythropoietin (rHuEPO) and darbepoetin alfa (DA) are key treatments for …