Paediatrics
Paediatrics

A systematic methodological evaluation of sepsis guidelines: Protocol for quality assessment and consistency of recommendations

Acta Anaesthesiol Scand. 2025 Jul;69(6):e70036. doi: 10.1111/aas.70036. ABSTRACT BACKGROUND: Sepsis is a leading cause of mortality worldwide, characterized by a dysregulated host response to infection. …

Advancing the Use of Longitudinal Electronic Health Records: Tutorial for Uncovering Real-World Evidence in Chronic Disease Outcomes

J Med Internet Res. 2025 May 12;27:e71873. doi: 10.2196/71873. ABSTRACT Managing chronic diseases requires ongoing monitoring of disease activity and therapeutic responses to optimize treatment …

MHCIIhiLYVE1loCCR2hi Interstitial Macrophages Promote Medial Fibrosis in Pulmonary Arterioles and Contribute to Pulmonary Hypertension

Circ Res. 2025 May 13. doi: 10.1161/CIRCRESAHA.125.326173. Online ahead of print. ABSTRACT BACKGROUND: Pulmonary hypertension (PH) is a lethal disease characterized in part by progressive …

Alarming findings of psycho-socio-spiritual interventions on physical, mental, and social health for children with cancer and their families in low- and middle-income countries: a meta-analysis

Front Psychiatry. 2025 Apr 28;16:1533599. doi: 10.3389/fpsyt.2025.1533599. eCollection 2025. ABSTRACT BACKGROUND: Children residing in low- and middle-income countries (LMICs) are at a higher risk of …

Using an in-situ Simulation Model to Identify Deviations from Guideline-Based Management of Pediatric Status Epilepticus in Community Emergency Departments

Open Access Emerg Med. 2025 May 7;17:165-171. doi: 10.2147/OAEM.S507770. eCollection 2025. ABSTRACT BACKGROUND: Children with epilepsy are often presented to Community Emergency Departments (CEDs) for …