Paediatrics
Paediatrics

The safety and feasibility of multiple intrathecal injections of allogenic NK cells in pediatrics with refractory/recurrent brain tumors

BMC Cancer. 2025 May 27;25(1):952. doi: 10.1186/s12885-025-14314-6. ABSTRACT BACKGROUND: Pediatric glioma is a rare condition that can lead to significant mortality and morbidity due to …

Impact of antimicrobial exposure at delivery and siblings on early Bifidobacterium succession and allergy development up to 24 months of age

BMC Microbiol. 2025 May 28;25(1):332. doi: 10.1186/s12866-025-04056-7. ABSTRACT BACKGROUND: Allergic diseases such as asthma, eczema, and food allergies are rising globally. The infant gut microbiota, …

ABCC2 as a novel covariate influencing oxcarbazepine pharmacokinetics in pediatric epilepsy: Insights from population modeling

Drug Metab Dispos. 2025 May 2;53(6):100090. doi: 10.1016/j.dmd.2025.100090. Online ahead of print. ABSTRACT This study set out to establish a population pharmacokinetic (PPK) model of …

Intravenous Dabigatran Provides Effective, Reversible Anticoagulation for Cardiopulmonary Bypass in a Sheep Model

Anesthesiology. 2025 May 27. doi: 10.1097/ALN.0000000000005580. Online ahead of print. ABSTRACT BACKGROUND: Heparin is the standard anticoagulant used during Cardiopulmonary Bypass (CPB). However, there are …

Postoperative radiotherapy in subtotally-resected recurrent WHO grade 1 meningiomas with intermediate-/high-risk molecular profiles

Neuro Oncol. 2025 May 27:noaf125. doi: 10.1093/neuonc/noaf125. Online ahead of print. ABSTRACT BACKGROUND: Meningiomas represent the most common primary intracranial tumors in adults, with WHO …