Paediatrics
Paediatrics

Preemptive Acetaminophen for Postoperative Analgesia in Children Undergoing Surgery: A Systematic Review and Meta-Analysis

Pain Physician. 2025 Jul;28(4):E359-E369. ABSTRACT BACKGROUND: Preemptive analgesia is an antinociceptive intervention aimed at inhibiting hyperexcitability in both the peripheral and central nervous systems, diminishing …

Extrachromosomal DNA-Driven Oncogene Dosage Heterogeneity Promotes Rapid Adaptation to Therapy in MYCN-Amplified Cancers

Cancer Discov. 2025 Aug 7:OF1-OF24. doi: 10.1158/2159-8290.CD-24-1738. Online ahead of print. ABSTRACT Extrachromosomal DNA (ecDNA) amplification enhances intercellular oncogene dosage variability and accelerates tumor evolution …

Guideline-Based Digital Exercise Interventions for Reducing Body Weight and Fat and Promoting Physical Activity in Adults With Overweight and Obesity: Systematic Review and Meta-Analysis

Interact J Med Res. 2025 Aug 7;14:e73656. doi: 10.2196/73656. ABSTRACT BACKGROUND: Digitally delivered physical exercise interventions are becoming increasingly popular in addressing the obesity epidemic. …

Ureteroscopy vs Shockwave Lithotripsy to Remove Kidney Stones in Children and Adolescents: A Nonrandomized Clinical Trial

JAMA Netw Open. 2025 Aug 1;8(8):e2525789. doi: 10.1001/jamanetworkopen.2025.25789. ABSTRACT IMPORTANCE: Most children and adolescents with kidney and ureteral stones are treated with ureteroscopy, despite the …

Using the CARD system for university-based pop-up vaccination clinics: A two-stage hybrid effectiveness-implementation study

Hum Vaccin Immunother. 2025 Dec;21(1):2509484. doi: 10.1080/21645515.2025.2509484. Epub 2025 Aug 7. ABSTRACT Mass vaccination clinics efficiently vaccinate large numbers of people. The CARD system (Comfort, …

An eye tracking analysis for the assessment of visual attention and preferences of children related to the dentist and dental operatory-a cross-sectional pilot study

Eur Arch Paediatr Dent. 2025 Aug 7. doi: 10.1007/s40368-025-01089-4. Online ahead of print. ABSTRACT PURPOSE: The study aimed to use eye tracking technology to assess …

Impact of Extracorporeal Membrane Oxygenation Life Support on Vancomycin Population Pharmacokinetics in Critical Illness: A Systematic Review

Clin Drug Investig. 2025 Aug 7. doi: 10.1007/s40261-025-01449-4. Online ahead of print. ABSTRACT BACKGROUND: An extracorporeal membrane oxygenation (ECMO) device represents an additional functional body …

Pulmonary outcomes of pediatric patients with postinfectious bronchiolitis obliterans treated with pulse methylprednisolone and intravenous immunoglobulin: a single-center cohort study

Eur J Pediatr. 2025 Aug 7;184(9):536. doi: 10.1007/s00431-025-06378-0. ABSTRACT Postinfectious bronchiolitis obliterans (PIBO) is a severe chronic pulmonary disorder in children, characterized by irreversible airway …

Indications for Pediatric Enucleations of Non-Retinoblastoma Globes in Saudi Arabia with Clinical and Radiological Correlation To Final Histopathological Diagnosis

J Epidemiol Glob Health. 2025 Aug 7;15(1):105. doi: 10.1007/s44197-025-00449-z. NO ABSTRACT PMID:40773126 | DOI:10.1007/s44197-025-00449-z

Retrospective observational study of the magnetic resonance imaging features of MPV17-related mitochondrial DNA depletion syndrome

Pediatr Radiol. 2025 Aug 7. doi: 10.1007/s00247-025-06341-z. Online ahead of print. ABSTRACT BACKGROUND: MPV17-related mitochondrial deoxyribonucleic acid (DNA) maintenance defects present in most affected individuals …