Paediatrics
Paediatrics

Spatial host-microbiome profiling demonstrates bacterial-associated host transcriptional alterations in pediatric ileal Crohn’s disease

Microbiome. 2025 Aug 23;13(1):189. doi: 10.1186/s40168-025-02178-8. ABSTRACT BACKGROUND: Crohn’s disease (CD) is a chronic inflammatory bowel disease involving complex relationships between the gut microbiome and …

Genetically predicted interleukin 7 levels and neuroblastoma risk combined with analysis of radiation therapy timing effects

Discov Oncol. 2025 Aug 23;16(1):1601. doi: 10.1007/s12672-025-03336-y. ABSTRACT BACKGROUND: The causal relationship between interleukin-7 levels and neuroblastoma risk remains unclear, and optimal radiation therapy timing …

Inflammatory factor CCL2 enhances the interaction between monocyte-macrophage cells and liver parenchymal cells to promote liver inflammation and fibrosis in biliary atresia

BMC Pediatr. 2025 Aug 23;25(1):643. doi: 10.1186/s12887-025-05984-z. ABSTRACT BACKGROUND: Liver fibrosis in biliary atresia (BA) progresses rapidly and has distinct characteristics; however, current studies have …

L-shaped association between fibrinogen to serum albumin ratio and all-cause mortality among critically ill children: a retrospective cohort study

BMC Pediatr. 2025 Aug 23;25(1):644. doi: 10.1186/s12887-025-06011-x. ABSTRACT BACKGROUND: While elevated fibrinogen-to-albumin ratio (FAR) correlates with all-cause mortality in adults, its prognostic value in pediatric …

Developing a Protocol for Therapeutic Plasma Exchange in Tandem With Continuous Renal Replacement Therapy (CRRT) and ExtraCorporeal Membrane Oxygenation (ECMO) in Pediatric Patients

J Clin Apher. 2025 Aug;40(4):e70051. doi: 10.1002/jca.70051. ABSTRACT Therapeutic plasma exchange (TPE) in pediatric patients presents many challenges, including management of a large extracorporeal volume …