Paediatrics
Paediatrics

Association between preoperative neutrophil-to-lymphocyte ratio and length of stay in pediatric patients undergoing laparoscopic appendectomy: a retrospective cohort study

BMC Pediatr. 2025 Aug 30;25(1):668. doi: 10.1186/s12887-025-06043-3. ABSTRACT BACKGROUND: Although the neutrophil-to-lymphocyte ratio (NLR) has demonstrated diagnostic utility in appendicitis, its predictive value for postoperative …

Hybrid Population Pharmacokinetic-Machine Learning Modeling to Predict Infliximab Pharmacokinetics in Pediatric and Young Adult Patients with Crohn’s Disease

Clin Pharmacokinet. 2025 Aug 30. doi: 10.1007/s40262-025-01564-7. Online ahead of print. ABSTRACT BACKGROUND AND OBJECTIVE: Population pharmacokinetic (PK) model-based Bayesian estimation is widely used for …

Case Report of Pediatric HPCA-Associated Dystonia: Analysis of Ca(2+) and K(+) Channel Dynamics and Experience With Pallidal Deep Brain Stimulation

Pediatr Neurol. 2025 Aug 7;172:46-52. doi: 10.1016/j.pediatrneurol.2025.07.020. Online ahead of print. ABSTRACT BACKGROUND: Biallelic pathogenic variants in the HPCA gene cause HPCA-associated dystonia (DYT-HPCA), a …

Preferences of Adolescents and Young Adults With Epilepsy and Caregivers on Reproductive Health Counseling by Neurologists: A Concept Mapping Study

Pediatr Neurol. 2025 Aug 11;172:35-45. doi: 10.1016/j.pediatrneurol.2025.08.002. Online ahead of print. ABSTRACT OBJECTIVE: To ascertain reproductive health counseling priorities of adolescent and young adult women …

Protocol for plasma membrane enrichment by ultracentrifugation for mass spectrometry of cell lines, xenografts, and patient tumors

STAR Protoc. 2025 Aug 28;6(3):104049. doi: 10.1016/j.xpro.2025.104049. Online ahead of print. ABSTRACT The success of immunotherapies hinges on identifying targetable cell surface proteins expressed in …

Infectious Complications During Reinduction in Children with Relapsed Acute Lymphoblastic Leukemia: A Descriptive Analysis

Pediatr Hematol Oncol. 2025 Aug 30:1-11. doi: 10.1080/08880018.2025.2550516. Online ahead of print. ABSTRACT Children with relapsed acute lymphoblastic leukemia (ALL) face higher rates of infection …