Paediatrics
Paediatrics

Control of Allergic Rhinitis and Asthma Test for Children (CARATkids): A systematic review and meta-analysis of its measurement properties

Pediatr Allergy Immunol. 2025 Sep;36(9):e70191. doi: 10.1111/pai.70191. ABSTRACT Control of Allergic Rhinitis and Asthma Test for Children (CARATkids) is the first patient-reported outcome measure (PROM) …

Improving immune-related health outcomes post-cesarean birth with a gut microbiome-based program: A randomized controlled trial

Pediatr Allergy Immunol. 2025 Sep;36(9):e70182. doi: 10.1111/pai.70182. ABSTRACT BACKGROUND: Infants born via Cesarean section (C-section) often have a distinct gut microbiome and higher risks of …

CLDN10-driven lineage decision in an amnion and primordial germ cell progenitor at the amnion-epiblast boundary in primates

Genome Biol. 2025 Sep 2;26(1):263. doi: 10.1186/s13059-025-03751-y. ABSTRACT BACKGROUND: A growing body of evidence from primate embryos as well as in vitro systems supports the …

Could scoliosis at the age of 7 months be a manifestation of progressive pseudorheumatoid dysplasia? A case report

J Med Case Rep. 2025 Sep 2;19(1):437. doi: 10.1186/s13256-025-05425-6. ABSTRACT BACKGROUND: Progressive pseudorheumatoid dysplasia is a rare genetic skeletal disease that usually affects children between …

Evaluating the causal effect of circulating proteome on the risk of Juvenile idiopathic arthritis: an omics pipeline study

Pediatr Rheumatol Online J. 2025 Sep 2;23(1):91. doi: 10.1186/s12969-025-01140-0. ABSTRACT BACKGROUND: Genome-wide association studies (GWAS) have pinpointed a multitude of risk loci associated with Juvenile …

Prenatal diagnosis of rare genetic disorders: fourteen years’ experience of a tertiary genetic centre from India

Orphanet J Rare Dis. 2025 Sep 2;20(1):471. doi: 10.1186/s13023-025-04003-9. ABSTRACT BACKGROUND: Rare genetic disorders are increasingly diagnosed due to advancing genetic technology, whilst, treatment for …

Connexin hemichannel blockade by abEC1.1 disrupts glioblastoma progression, suppresses invasiveness, and reduces hyperexcitability in preclinical models

Cell Commun Signal. 2025 Sep 2;23(1):391. doi: 10.1186/s12964-025-02370-1. ABSTRACT BACKGROUND: Connexin (Cx) hemichannels (HCs) contribute to glioblastoma (GBM) progression by facilitating intercellular communication and releasing …

A comparison of the impact of nurse-led education and telehealth interventions on mental health outcomes for ambulatory patients in Saudi Arabia

BMC Nurs. 2025 Sep 2;24(1):1155. doi: 10.1186/s12912-025-03789-0. ABSTRACT BACKGROUND: Mental health disorders, including depression, anxiety, and pain, are prevalent among ambulatory patients. Nurse-Led Education and …