Paediatrics
Paediatrics

Enhanced accuracy and sensitivity in detecting FMR1 CGG repeats: a multicenter evaluation of a novel PCR-capillary electrophoresis assay

World J Pediatr. 2025 Sep 12. doi: 10.1007/s12519-025-00977-5. Online ahead of print. ABSTRACT BACKGROUND: Fragile X syndrome (FXS) is primarily caused by the expansion of …

PD1/PDL1 and TIM3/Gal9 expression in acute lymphoblastic leukemia: Gal-9 expression on leukemia stem cells as an independent prognostic parameter

BMC Cancer. 2025 Sep 12;25(1):1421. doi: 10.1186/s12885-025-14856-9. ABSTRACT The introduction of immune checkpoint inhibitors (ICI) which are designed not to activate the immune system to …

Impact of intraoperative radiotherapy vs postoperative radiotherapy on survival in early-stage breast cancer patients

Eur Radiol. 2025 Sep 12. doi: 10.1007/s00330-025-11879-5. Online ahead of print. ABSTRACT OBJECTIVES: Intraoperative radiotherapy (IORT), has been debated regarding its long-term efficacy in breast …

Automatic segmentation of pediatric brain tumors in the posterior fossa and the surrounding anatomy: an efficient method for optimized preoperative planning and patient education

J Neurosurg Pediatr. 2025 Sep 12:1-8. doi: 10.3171/2025.5.PEDS24567. Online ahead of print. ABSTRACT OBJECTIVE: This study aimed to develop and evaluate an automated segmentation model …

Comparison of real-world kidney outcomes with predicted outcomes at the time of diagnosis and post-biopsy in a cohort of children with IgA nephropathy

J Bras Nefrol. 2025 Jul-Sep;47(3):e20240260. doi: 10.1590/2175-8239-JBN-2024-0260en. ABSTRACT INTRODUCTION: IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis, with a variable clinical course. …

Cross-Site Predictions of Readmission After Psychiatric Hospitalization With Mood or Psychotic Disorders: Retrospective Study

JMIR Ment Health. 2025 Sep 12;12:e71630. doi: 10.2196/71630. ABSTRACT BACKGROUND: Patients with mood or psychotic disorders experience high rates of unplanned hospital readmissions. Predicting the …