Ivermectin dosing for children under 2 years
J Antimicrob Chemother. 2025 Sep 23:dkaf344. doi: 10.1093/jac/dkaf344. Online ahead of print. ABSTRACT OBJECTIVES: Ivermectin is effective against scabies but not licensed for children weighing …
Paediatrics
Population pharmacokinetics and dosing optimization of cefoselis in paediatric patients with haematological malignancies
J Antimicrob Chemother. 2025 Sep 23:dkaf363. doi: 10.1093/jac/dkaf363. Online ahead of print. ABSTRACT BACKGROUND: Cefoselis is a fourth-generation cephalosporin primarily indicated for infections caused by …
Distinct lung functional, histological and cell senescence signatures in the single and repetitive bleomycin mouse models of idiopathic pulmonary fibrosis
Physiol Rep. 2025 Sep;13(18):e70560. doi: 10.14814/phy2.70560. ABSTRACT This study aimed to comprehensively compare the lung disease phenotypes between single-dose and repetitive-dose bleomycin (BLEO)-induced mouse models …
Quieting Cholinergic Neurons in Dystonia
Mov Disord. 2025 Sep 23. doi: 10.1002/mds.70045. Online ahead of print. NO ABSTRACT PMID:40985130 | DOI:10.1002/mds.70045
Real-life experience with a “modified-MEMMAT” regimen for relapsed medulloblastoma
Ther Adv Med Oncol. 2025 Sep 20;17:17588359251344002. doi: 10.1177/17588359251344002. eCollection 2025. ABSTRACT BACKGROUND: Medulloblastoma (MB) relapse is typically resistant to available treatments. An emerging alternative …
Electrodiagnostic and Functional Biomarkers for Non-Ambulatory Children With Late-Onset Spinal Muscular Atrophy
Muscle Nerve. 2025 Sep 23. doi: 10.1002/mus.70030. Online ahead of print. ABSTRACT INTRODUCTION/AIMS: Identifying sensitive response measures is crucial for evaluating treatment efficacy in SMA …
Physiologically Based Pharmacokinetic Modeling and Dose Optimization of Linezolid in Pediatric Patients With Renal Impairment
Drug Des Devel Ther. 2025 Sep 17;19:8427-8440. doi: 10.2147/DDDT.S525400. eCollection 2025. ABSTRACT OBJECTIVE: Linezolid (LZD), a commonly used antimicrobial agent in clinical practice, has not …
Clinical Application of Noninvasive Prenatal Testing in Singleton Pregnancy with and without in vitro Fertilization: A 6-year Observational Study at a Single Tertiary Center
Int J Womens Health. 2025 Sep 17;17:3067-3076. doi: 10.2147/IJWH.S547427. eCollection 2025. ABSTRACT BACKGROUND: Studies on the use of noninvasive prenatal testing (NIPT) in pregnancies conceived …
Comparison of Long-Term Revision Rates and Health Care Utilization Between Standalone Balloon Sinus Dilation and Endoscopic Sinus Surgery in Chronic Rhinosinusitis Patients Without Nasal Polyps: Is the Balloon Value Proposition Overinflated?
Am J Rhinol Allergy. 2025 Sep 22:19458924251377259. doi: 10.1177/19458924251377259. Online ahead of print. ABSTRACT BackgroundPrevious research has reported inconsistent results when evaluating long-term revision rates …
Comparison of reduced field-of-view DWI with conventional DWI for machine learning-based assessment of lymphovascular invasion in rectal cancer
Med Phys. 2025 Oct;52(10):e70015. doi: 10.1002/mp.70015. ABSTRACT BACKGROUND: Lymphovascular invasion (LVI) is an important prognostic factor of rectal cancer and influences treatment planning. MRI-based radiomic …