Paediatrics
Paediatrics

Time to hyperglycemic emergency and its predictors among adult diabetic patients on follow-up in four public hospitals, in central Ethiopia

Sci Rep. 2025 Sep 30;15(1):33844. doi: 10.1038/s41598-025-06186-4. ABSTRACT Diabetes mellitus is a common metabolic disorder resulting from either insulin deficiency or ineffectiveness. Hyperglycemic Emergency are …

Artificial intelligence based platform for the automatic and simultaneous explainable detection of apnoea, oxygen desaturation, and artefacts in paediatric polygraphy exams (REST)

Sci Rep. 2025 Sep 30;15(1):34024. doi: 10.1038/s41598-025-13630-y. ABSTRACT The gold standard for the diagnosis of sleep apnoea (SA) is polysomnography, consisting of overnight in-lab tests, …

Contribution of leukocyte telomere length to cardiovascular disease onset from genome-wide cross-trait analysis

Nat Commun. 2025 Sep 30;16(1):8677. doi: 10.1038/s41467-025-63707-5. ABSTRACT Telomere shortening is a well-established marker of cellular aging and genomic instability. While the relationship between leukocyte …

RNA-mediated condensation of TFE3 oncofusions facilitates transcriptional hub formation to promote translocation renal cell carcinoma

Nat Commun. 2025 Sep 30;16(1):8712. doi: 10.1038/s41467-025-63761-z. ABSTRACT Transcription factor E3 (TFE3) oncofusions are frequently detected in the Microphthalmia transcription factor (MiT) family translocation renal …

Oxidative stress-induced intervertebral disc remodelling and elevated stiffness drive idiopathic scoliosis in preclinical models

Nat Commun. 2025 Sep 30;16(1):8719. doi: 10.1038/s41467-025-63742-2. ABSTRACT Adolescent idiopathic scoliosis (AIS) is the most prevalent pediatric spine disorder, developing in the absence of obvious …