Paediatrics
Paediatrics

CDKN2A deletion in p16-negative/HPV-positive head and neck squamous cell carcinoma: Highlighting the molecular basis behind the limitation of relying on p16 immunohistochemistry as a surrogate marker for HPV involvement

Histopathology. 2025 Oct 9. doi: 10.1111/his.70021. Online ahead of print. ABSTRACT AIMS: Immunohistochemistry (IHC) for p16 is widely used as a surrogate marker for HPV …

Response by Gal et al to Letter Regarding Article, “Predictors of Neurodevelopmental and Mental Health Diagnoses in Congenital Heart Disease: A Danish Population-Based Cohort Study”

Circ Cardiovasc Qual Outcomes. 2025 Oct 9:e012690. doi: 10.1161/CIRCOUTCOMES.125.012690. Online ahead of print. NO ABSTRACT PMID:41064876 | DOI:10.1161/CIRCOUTCOMES.125.012690

Comparative Analysis of Immaturity CD Markers Expression between Pediatric and Adult Acute Lymphoblastic Leukemia: Insights and Implications for Diagnostic and Therapeutic Strategies

Acta Medica (Hradec Kralove). 2025;68(2):50-57. doi: 10.14712/18059694.2025.19. ABSTRACT OBJECTIVE: The objective of this study is to assess the expression levels of different immaturity CD markers …

Mucolipidosis type II and III: clinical spectrum, genetic landscape, and longitudinal outcomes in a pediatric cohort with six novel mutations

J Pediatr Endocrinol Metab. 2025 Oct 10. doi: 10.1515/jpem-2025-0352. Online ahead of print. ABSTRACT OBJECTIVES: Mucolipidosis (ML) type II α/β (I-cell disease) and type III …

Determination of the 50% and 95% effective dose of esketamine combined with propofol for intravenous sedation in pediatric circumcision: study protocol for a randomized controlled, double-blind, dose-finding clinical trial

Trials. 2025 Oct 8;26(1):393. doi: 10.1186/s13063-025-09159-0. ABSTRACT BACKGROUND: Pediatric circumcision is a common yet often distressing procedure due to the associated pain and emotional response …

Determinants of HIV related mortality in African children on antiretroviral therapy: clinical and immunological insights from a systematic review and meta-analysis

AIDS Res Ther. 2025 Oct 8;22(1):102. doi: 10.1186/s12981-025-00784-y. ABSTRACT BACKGROUND: The HIV epidemic in Africa is still a serious public health concern, particularly for children …