Esculin induces endoplasmic reticulum stress and drives apoptosis and ferroptosis in colorectal cancer via PERK regulating eIF2α/CHOP and Nrf2/HO-1 cascades
J Ethnopharmacol. 2024 Mar 30:118139. doi: 10.1016/j.jep.2024.118139. Online ahead of print. ABSTRACT ETHNOPHARMACOLOGICAL RELEVANCE: Cortex fraxini (also known as Qinpi), the bark of Fraxinus rhynchophylla …