Paediatrics
Paediatrics

Gut metabolome and microbiota signatures predict response to treatment with exclusive enteral nutrition in a prospective study in children with active Crohn’s disease

Am J Clin Nutr. 2024 Apr;119(4):885-895. doi: 10.1016/j.ajcnut.2023.12.027. Epub 2024 Feb 19. ABSTRACT BACKGROUND: Predicting response to exclusive enteral nutrition (EEN) in active Crohn’s disease …

Cognition after a 4-week high phenylalanine intake in adults with phenylketonuria – a randomized controlled trial

Am J Clin Nutr. 2024 Apr;119(4):908-916. doi: 10.1016/j.ajcnut.2023.11.007. Epub 2024 Feb 9. ABSTRACT BACKGROUND: Phenylketonuria (PKU) is an autosomal recessive metabolic disorder characterized by increased …

Utilizing the gut microbiome as a biomarker of response to dietary interventions in inflammatory bowel disease: moving toward precision nutrition

Am J Clin Nutr. 2024 Apr;119(4):868-869. doi: 10.1016/j.ajcnut.2024.01.022. Epub 2024 Feb 19. NO ABSTRACT PMID:38569783 | DOI:10.1016/j.ajcnut.2024.01.022

NODAL variants are associated with a continuum of laterality defects from simple D-transposition of the great arteries to heterotaxy

Genome Med. 2024 Apr 3;16(1):53. doi: 10.1186/s13073-024-01312-9. ABSTRACT BACKGROUND: NODAL signaling plays a critical role in embryonic patterning and heart development in vertebrates. Genetic variants …

The genetic basis of early-onset hereditary ataxia in Iran: results of a national registry of a heterogeneous population

Hum Genomics. 2024 Apr 3;18(1):35. doi: 10.1186/s40246-024-00598-5. ABSTRACT BACKGROUND: To investigate the genetics of early-onset progressive cerebellar ataxia in Iran, we conducted a study at …