Paediatrics
Paediatrics

PTSD Coach as an early mobile intervention to improve cancer-related anxiety and psychosocial oncology uptake in patients newly diagnosed with head and neck cancer: pilot randomized controlled trial

Pilot Feasibility Stud. 2024 Dec 21;10(1):153. doi: 10.1186/s40814-024-01556-7. ABSTRACT BACKGROUND: This pilot study aimed to provide supportive evidence for the feasibility of conducting a full-scale …

A novel conditioning regimen with pre-transplantation immunosuppression reduces the complication rates in hematopoietic stem cell transplantation in transfusion-dependent β-thalassemia

Stem Cell Res Ther. 2024 Dec 21;15(1):495. doi: 10.1186/s13287-024-04103-6. ABSTRACT BACKGROUND: Allo-HSCT is a curative therapy for patients with transfusion-dependent thalassemia (TDT). The high incidence …

International workshop: what is needed to ensure outcome measures for Rett syndrome are fit-for-purpose for clinical trials? June 7, 2023, Nashville, USA

Trials. 2024 Dec 21;25(1):845. doi: 10.1186/s13063-024-08678-6. ABSTRACT INTRODUCTION: The clinical, research and advocacy communities for Rett syndrome are striving to achieve clinical trial readiness, including …

Examination of the effect of treatment of severe early childhood caries and fluoride varnish applications on salivary oxidative stress biomarkers and antioxidants

BMC Oral Health. 2024 Dec 21;24(1):1536. doi: 10.1186/s12903-024-05185-7. ABSTRACT BACKGROUND: Saliva contains a variety of biochemical compounds, including antioxidants, and serves as the body’s first …

Systematic literature review on early detection of postoperative delirium in adult patients after cardiac surgery

J Cardiothorac Surg. 2024 Dec 21;19(1):678. doi: 10.1186/s13019-024-03173-0. ABSTRACT BACKGROUND: Postoperative delirium (POD) is a cognitive decline and attention deficit that can occur in patients …

RORA-neurodevelopmental disorder: a unique triad of developmental disability, cerebellar anomalies, and myoclonic seizures

Genet Med. 2024 Dec 17:101347. doi: 10.1016/j.gim.2024.101347. Online ahead of print. ABSTRACT PURPOSE: RORA encodes the RAR-related orphan receptor-α (RORα), playing a pivotal role in …