Paediatrics
Paediatrics

Genomic epidemiological analysis of a single-centre polyclonal outbreak of Serratia marcescens, Belgium, 2022 to 2023

Euro Surveill. 2024 Nov;29(48). doi: 10.2807/1560-7917.ES.2024.29.48.2400144. ABSTRACT Serratia marcescens is an opportunistic pathogen with a propensity to cause nosocomial outbreaks, particularly in neonatal intensive care …

Novel genomic variants influencing methotrexate delayed clearance in pediatric patients with acute lymphoblastic leukemia

Front Pharmacol. 2024 Nov 14;15:1480657. doi: 10.3389/fphar.2024.1480657. eCollection 2024. ABSTRACT BACKGROUND: Methotrexate (MTX) is the primary drug used in the treatment of pediatric acute lymphoblastic …

Allergic rhinitis management: a Delphi Consensus promoted by the Italian Society of Pediatric Allergy and Immunology (SIAIP)

Ital J Pediatr. 2024 Nov 28;50(1):254. doi: 10.1186/s13052-024-01824-5. ABSTRACT Allergic rhinitis (AR) is the most frequent IgE-mediated disease, mainly in children and adolescents. Management of …

A micro-costing study of mass-spectrometry based quantitative proteomics testing applied to the diagnostic pipeline of mitochondrial and other rare disorders

Orphanet J Rare Dis. 2024 Nov 29;19(1):443. doi: 10.1186/s13023-024-03462-w. ABSTRACT BACKGROUND: Mass spectrometry-based quantitative proteomics has a demonstrated utility in increasing the diagnostic yield of …

Routine use of patient-reported experience and outcome measures for children and young people: a scoping review

Syst Rev. 2024 Nov 28;13(1):293. doi: 10.1186/s13643-024-02706-x. ABSTRACT BACKGROUND: Patient-reported outcome measures (PROMs) measure people’s views of their health status whereas patient-reported experience measures (PREMs) …

Concordance between immunohistochemistry and MSI analysis for detection of MMR/MSI status in colorectal cancer patients

Diagn Pathol. 2024 Nov 29;19(1):155. doi: 10.1186/s13000-024-01571-5. ABSTRACT BACKGROUND: Recently, screening of colorectal cancer (CRC) patients for mismatch repair/microsatellite instability (MMR/MSI) status is widely practiced …