Age-Dependent Abundance of CYP450 Enzymes Involved in Metronidazole Metabolism: Application to Pediatric PBPK Modeling
Clin Pharmacol Ther. 2024 Jul 2. doi: 10.1002/cpt.3354. Online ahead of print. ABSTRACT The expression of cytochrome P450 (CYP) enzymes is highly variable and associated …