Updates in Trisomy 18
Neoreviews. 2025 Dec 1;26(12):e820-e834. doi: 10.1542/neo.26-12-082. ABSTRACT Aneuploidies represent some of the most common genetic abnormalities within the pediatric population. Among them, trisomies 13, 18, …
Neonatal Medicine
The glutamine metabolic switch influences the response of neonatal intestinal macrophages to breast milk
Cell Mol Gastroenterol Hepatol. 2025 Nov 28:101683. doi: 10.1016/j.jcmgh.2025.101683. Online ahead of print. ABSTRACT BACKGROUND & AIMS: Breast milk contains abundant glutamine and glutamate, yet …
Pregnancy Outcomes of Maternal Periconceptional Exposure to Glucagon-Like Peptide-1 Receptor Agonists: A Scoping Review of Evidence and Reporting Trends
J Obstet Gynaecol Can. 2025 Nov 28:103191. doi: 10.1016/j.jogc.2025.103191. Online ahead of print. ABSTRACT BACKGROUND: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have recently gained dramatic …
Bias and Disparities in Neonatal End-of-Life Care
Neoreviews. 2025 Dec 1;26(12):e865-e874. doi: 10.1542/neo.26-12-076. NO ABSTRACT PMID:41319972 | DOI:10.1542/neo.26-12-076
One Allergy, Two Paths: Navigating Penicillin Evaluation in Pregnant Patients Direct Challenges vs Penicillin Skin Testing in Pregnancy: A Controversies in Allergy Review
J Allergy Clin Immunol Pract. 2025 Nov 28:S2213-2198(25)01135-3. doi: 10.1016/j.jaip.2025.11.030. Online ahead of print. ABSTRACT Unverified penicillin allergy labels are common and can result in …
F-53B-induced placental vascular endothelial dysfunction leads to intrauterine growth retardation of fetal mice
Ecotoxicol Environ Saf. 2025 Nov 29;308:119467. doi: 10.1016/j.ecoenv.2025.119467. Online ahead of print. ABSTRACT Chlorinated polyfluoroalkyl ether sulfonic acid (Cl-PFESAs, trade name F-53B) is a perfluorinated …
Management of prematurity-associated lung disease from infancy through to adulthood
Lancet Respir Med. 2025 Nov 27:S2213-2600(25)00369-8. doi: 10.1016/S2213-2600(25)00369-8. Online ahead of print. ABSTRACT Preterm birth has lifelong pulmonary consequences, with many individuals developing prematurity-associated lung …
High Resolution Postmortem MRI Discovers Developing Structural Connectivity in the Human Ascending Arousal Network
Hum Brain Mapp. 2025 Dec 1;46(17):e70422. doi: 10.1002/hbm.70422. ABSTRACT Human arousal is essential to survival and mediated by the ascending arousal network (AAN) and its …
Twenty-year trends in fetal scalp-blood sampling and birth outcomes: A single-center retrospective cohort study of 40 309 women in labor
Acta Obstet Gynecol Scand. 2025 Nov 29. doi: 10.1111/aogs.70110. Online ahead of print. ABSTRACT INTRODUCTION: At Kuopio University Hospital (KUH), the rate of fetal blood …
Astragalus membranaceus injection activates mitophagy and protects mitochondrial function in chronic heart failure via inhibiting AKT/mTOR pathway
Sci Rep. 2025 Nov 28;15(1):42770. doi: 10.1038/s41598-025-27065-y. ABSTRACT To investigate the effects and mechanisms of Astragalus Membranaceus Injection (AMI) on mitophagy and mitochondrial function in …