Neonatal Medicine
Neonatal Medicine

Photostability of Topoisomerase I Inhibitor Conjugated IgG1 Antibody-Drug Conjugates: Characterization Study and Degradation Mechanism Analysis

Bioconjug Chem. 2025 Nov 22. doi: 10.1021/acs.bioconjchem.5c00485. Online ahead of print. ABSTRACT DNA topoisomerase I (TOP1) inhibitor-based antibody-drug conjugates (ADCs) incorporating photosensitive camptothecin (CPT) analogs …

The cytotoxicity of gomesin peptides is mediated by the glycosphingolipid pathway and lipid-cholesterol interactions

Cell Death Discov. 2025 Nov 21;11(1):538. doi: 10.1038/s41420-025-02817-x. ABSTRACT Gomesins (AgGom and HiGom) are therapeutically promising spider-derived peptides that target a specific phospholipid composition (3PC:1PS:1Chol) …

Perinatal equipment, medication and specialized formula shortages: Defining the challenge and exploring ethical solutions

Semin Perinatol. 2025 Nov 21:152187. doi: 10.1016/j.semperi.2025.152187. Online ahead of print. ABSTRACT Medication, equipment, and formula shortages have become commonplace in the neonatal intensive care …

Association of early respiratory support with mortality and bronchopulmonary dysplasia in very-low-birth-weight preterm infants

Pediatr Neonatol. 2025 Nov 13:S1875-9572(25)00201-3. doi: 10.1016/j.pedneo.2025.06.010. Online ahead of print. ABSTRACT BACKGROUND: Bronchopulmonary dysplasia (BPD) significantly impacts neonatal care. Early risk identification is vital …

Effects of Digital Mindfulness Training for Couples on Psychological Distress and Infant Neuropsychological Development: Randomized Controlled Trial

J Med Internet Res. 2025 Nov 21;27:e77260. doi: 10.2196/77260. ABSTRACT BACKGROUND: Maternal psychological distress during pregnancy is associated with unfavorable infant outcomes. Although mindfulness-based interventions …

Association between maternal and neonatal biochemical variables at delivery in pregnancies complicated by hypertensive disorders: a retrospective chart review in a tertiary referral unit

BMJ Open. 2025 Nov 21;15(11):e097603. doi: 10.1136/bmjopen-2024-097603. ABSTRACT OBJECTIVE: To examine the association between maternal and neonatal biochemical variables in babies born to mothers with …