Indian J Med Microbiol. 2024 Aug 9:100703. doi: 10.1016/j.ijmmb.2024.100703. Online ahead of print.
ABSTRACT
Multidrug -resistant tuberculosis (MDRTB) is a serious threat to mankind. India has the highest number of MDRTB cases, although majority remain undiagnosed due to inadequate diagnostic infrastructure, leading to increased community transmission and mortality. This one-year observational retrospective study highlighted the effectiveness of the National Tuberculosis Elimination Program (NTEP) for prompt detection of drug- resistant TB by GeneXpert MTB/RIF assay and revealed its associated clinico- epidemiological factors. The overall detection rates of MTB and RRTB were 20.70% and 20.86% respectively. The pediatric population had 7.69% rifampicin resistance, and HIV was strongly associated with the development of TB and RRTB (P<0.01).
PMID:39128730 | DOI:10.1016/j.ijmmb.2024.100703
