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NUDT21 Drives T-Cell Acute Lymphoblastic Leukemia Through Dual Regulation of Alternative Polyadenylation and Transcriptional Activation

Adv Sci (Weinh). 2026 Apr 2:e20693. doi: 10.1002/advs.202520693. Online ahead of print. ABSTRACT T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy with limited …

Tirzepatide and metformin effects on hunger and BMI in an adolescent with hyperphagia and severe obesity due to MC4R Deficiency: a case report

Obes Facts. 2026 Apr 2:1-13. doi: 10.1159/000551729. Online ahead of print. ABSTRACT INTRODUCTION: Tirzepatide, a dual GLP-1/GIP receptor agonist, is recently approved for the treatment …

Analysis of the Impact of Preterm Premature Rupture of Membranes (PPROM) on Maternal and Infant Outcomes and Countermeasures

Int J Womens Health. 2026 Jan 15;18:534571. doi: 10.2147/IJWH.S534571. eCollection 2026. ABSTRACT OBJECTIVE: This study aimed to analyze the risk factors for Preterm Premature Rupture …

Physics-informed graph neural networks for robust cross-patient epileptic seizure prediction via chimera state detection

PLoS One. 2026 Apr 2;21(4):e0345470. doi: 10.1371/journal.pone.0345470. eCollection 2026. ABSTRACT BACKGROUND: Epilepsy affects approximately 50 million individuals worldwide, with 30% experiencing drug-resistant seizures despite optimal …

Cross-cultural adaptation and psychometric validation of the Turkish Dusseldorf Orthorexia Scale in adolescents

Eat Weight Disord. 2026 Apr 2. doi: 10.1007/s40519-026-01847-3. Online ahead of print. ABSTRACT PURPOSE: Orthorexia nervosa (ON) is characterized by an excessive preoccupation with healthy …

Uncovering causal associations between plasma proteins and psychiatric disorders and identifying comorbidity biomarkers: a mendelian randomization study

Eur Arch Psychiatry Clin Neurosci. 2026 Apr 2. doi: 10.1007/s00406-026-02227-9. Online ahead of print. NO ABSTRACT PMID:41925857 | DOI:10.1007/s00406-026-02227-9

Trial tribulations: Lessons learned from an unsuccessful pilot trial of Behavioural Activation in young people with early or emerging psychosis at a regional mental health service

Australas Psychiatry. 2026 Apr 2:10398562261436366. doi: 10.1177/10398562261436366. Online ahead of print. ABSTRACT AimThe experience of conducting an unsuccessful pilot trial of behavioural activation (BA) to …