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The Pharmacokinetics and Relative Bioavailability of a Mini-Tablet of Mercaptopurine, a Novel Formulation for Use in Children with Acute Lymphoblastic Leukemia

J Clin Pharmacol. 2026 Apr;66(4):e70178. doi: 10.1002/jcph.70178. ABSTRACT A novel 5 mg mini-tablet formulation of mercaptopurine (6-MP) was developed to provide flexible and accurate doses …

Technical Success and Adverse Events Associated With Percutaneous Carotid Artery Access for Transcatheter Procedures in Infants

Catheter Cardiovasc Interv. 2026 Apr 3. doi: 10.1002/ccd.70601. Online ahead of print. ABSTRACT BACKGROUND: Demand for transcatheter interventions in small neonates continues to increase. Percutaneous …

Health-related quality of life and associated factors in Chinese pediatric patients with beta-thalassemia major receiving transfusion and iron chelation therapy: a cross-sectional study

Expert Rev Hematol. 2026 Apr 3:1-7. doi: 10.1080/17474086.2026.2654712. Online ahead of print. ABSTRACT BACKGROUND: This cross-sectional study assessed health-related quality of life (HRQOL) outcomes and …

Hypothalamic obesity in adults with craniopharyngiomas: prevalence and risk factors before and after neurosurgical treatment

Zh Vopr Neirokhir Im N N Burdenko. 2026;90(2):77-84. doi: 10.17116/neiro20269002177. ABSTRACT Hypothalamic obesity (weight gain due to hypothalamic damage) is a common complication of surgical …

Syndemics of complex risk factors in adolescents: findings from the youth risk behavior survey, 2021

Npj Ment Health Res. 2026 Apr 2;5(1):23. doi: 10.1038/s44184-026-00203-8. ABSTRACT Syndemic theory posits that multiple, interconnected health behaviors-such as substance use, anxiety, depression, sexual risk …

Optimized multichannel 4 mA vs conventional transcranial direct current stimulation for major depressive disorder: A randomized sham-controlled trial

Mol Psychiatry. 2026 Apr 2. doi: 10.1038/s41380-026-03560-0. Online ahead of print. ABSTRACT Major depressive disorder is a prevalent mental condition and the second most disabling …

Outcomes of paediatric medical stabilisation admissions for restrictive eating disorders: a multicentre evaluation

Arch Dis Child. 2026 Apr 2:archdischild-2025-330149. doi: 10.1136/archdischild-2025-330149. Online ahead of print. ABSTRACT Eating disorders (ED) are associated with mortality and morbidity. The outcomes of …

Exploring the relationship between emotional instability and suicidal ideation: A longitudinal study in adolescents with depression

J Psychiatr Res. 2026 Mar 24;198:234-239. doi: 10.1016/j.jpsychires.2026.03.030. Online ahead of print. ABSTRACT This longitudinal study employed Ecological Momentary Assessment (EMA) to investigate the dynamic …