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THBS2 + cancer-associated fibroblasts promote EMT leading to oxaliplatin resistance via COL8A1-mediated PI3K/AKT activation in colorectal cancer

Mol Cancer. 2024 Dec 28;23(1):282. doi: 10.1186/s12943-024-02180-y. ABSTRACT Cancer-associated fibroblasts (CAFs) exert multiple tumor-promoting functions and are key contributors to drug resistance. The mechanisms by …

Letter to the Editor Regarding “Effectiveness and Safety of High-Dose Tranexamic Acid in Adolescent Idiopathic Scoliosis Surgery: A Meta-Analysis and Systematic Review”

World Neurosurg. 2024 Dec 17;193:271. doi: 10.1016/j.wneu.2024.09.070. Online ahead of print. NO ABSTRACT PMID:39732006 | DOI:10.1016/j.wneu.2024.09.070

Aicardi-Goutières syndrome type 6: report of ADAR variant and clinical outcome after ruxolitinib treatment in the neonatal period

Pediatr Rheumatol Online J. 2024 Dec 28;22(1):110. doi: 10.1186/s12969-024-01036-5. ABSTRACT BACKGROUND: Aicardi-Goutières Syndrome is a monogenic type 1 interferonopathy with infantile onset, characterized by a …

Feasibility of the use of Kangaroo mother care in the transfer of preterm and low-birth-weight infants: a two-arm nonrandomized controlled cluster feasibility study of neonatal transport in Cape Coast, Ghana

BMC Pediatr. 2024 Dec 28;24(1):842. doi: 10.1186/s12887-024-05340-7. ABSTRACT BACKGROUND: Despite progress made towards SDG 3, sub-Saharan Africa lags behind the rest of the world, accounting …

Association between serum albumin levels at admission and clinical outcomes in pediatric intensive care units: a multi-center study

BMC Pediatr. 2024 Dec 28;24(1):844. doi: 10.1186/s12887-024-05331-8. ABSTRACT BACKGROUND: Albumin, a vital component in regulating human blood oncotic pressure, plays an important role in the …

Evaluation of dentists’ clinical practices and antibiotic use in managing endodontic emergencies in Karachi, Pakistan: a cross-sectional survey

BMC Oral Health. 2024 Dec 28;24(1):1565. doi: 10.1186/s12903-024-05357-5. ABSTRACT BACKGROUND: Endodontic emergencies, often presented as acute pain or swelling, constitute a substantial challenge in dental …