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Neonatal Medicine

Impact of LS Mutation on Pharmacokinetics of Preventive HIV Broadly Neutralizing Monoclonal Antibodies: A Cross-Protocol Analysis of 16 Clinical Trials in People without HIV

Pharmaceutics. 2024 Apr 27;16(5):594. doi: 10.3390/pharmaceutics16050594. ABSTRACT Monoclonal antibodies are commonly engineered with an introduction of Met428Leu and Asn434Ser, known as the LS mutation, in …

Neonatal Medicine

BCG Vaccination-Associated Lower HbA1c and Increased CD25 Expression on CD8+ T Cells in Patients with Type 1 Diabetes in Ghana

Vaccines (Basel). 2024 Apr 24;12(5):452. doi: 10.3390/vaccines12050452. ABSTRACT BCG vaccination affects other diseases beyond tuberculosis by unknown-potentially immunomodulatory-mechanisms. Recent studies have shown that BCG vaccination …

Neonatal Medicine

Safety and Efficacy of Nirsevimab in a Universal Prevention Program of Respiratory Syncytial Virus Bronchiolitis in Newborns and Infants in the First Year of Life in the Valle d’Aosta Region, Italy, in the 2023-2024 Epidemic Season

Vaccines (Basel). 2024 May 17;12(5):549. doi: 10.3390/vaccines12050549. ABSTRACT Respiratory syncytial virus (RSV) bronchiolitis remains a significant global health burden, particularly in newborns and infants during …

Neonatal Medicine

Developing Next-Generation Live Attenuated Vaccines for Porcine Epidemic Diarrhea Using Reverse Genetic Techniques

Vaccines (Basel). 2024 May 19;12(5):557. doi: 10.3390/vaccines12050557. ABSTRACT Porcine epidemic diarrhea virus (PEDV) is the etiology of porcine epidemic diarrhea (PED), a highly contagious digestive …

Neonatal Medicine

The Potential of Fecal Volatile Organic Compound Analysis for the Early Diagnosis of Late-Onset Sepsis in Preterm Infants: A Narrative Review

Sensors (Basel). 2024 May 16;24(10):3162. doi: 10.3390/s24103162. ABSTRACT Early diagnosis and treatment of late-onset sepsis (LOS) is crucial for survival, but challenging. Intestinal microbiota and …

Neonatal Medicine

Characterization of Natural Killer Cell Profile in a Cohort of Infected Pregnant Women and Their Babies and Its Relation to CMV Transmission

Viruses. 2024 May 14;16(5):780. doi: 10.3390/v16050780. ABSTRACT Human cytomegalovirus (CMV) is a common herpesvirus causing lifelong latent infection in most people and is a primary …

Paediatrics

Transnasal Endoscopy Acquires Esophageal Biopsies Adequate for Comprehensive Pathology Evaluation in Patients With Eosinophilic Esophagitis

Pediatr Dev Pathol. 2024 May 25:10935266241255723. doi: 10.1177/10935266241255723. Online ahead of print. ABSTRACT BACKGROUND: Transnasal endoscopy (TNE) does not require general anesthesia, an attractive characteristic …