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Child And Adolescent Mental Health

Early adolescent perceived friendship quality aids affective and neural responses to social inclusion and exclusion in young adults with and without adverse childhood experiences

Soc Cogn Affect Neurosci. 2024 Jun 21:nsae044. doi: 10.1093/scan/nsae044. Online ahead of print. ABSTRACT Friendships increase mental wellbeing and resilient functioning in young people with …

Paediatrics

Understanding the outcome and management of children aged 2-59 months with chest indrawing pneumonia: a study protocol for an observational study in Ethiopia, India, Nigeria, Pakistan, Uganda and Zambia

BMJ Open. 2024 Jun 19;14(6):e084350. doi: 10.1136/bmjopen-2024-084350. ABSTRACT INTRODUCTION: Childhood pneumonia is a leading cause of morbidity and mortality among children aged 2-59 months, particularly …

Paediatrics

Cohort profile: the ‘Biomarkers of heterogeneity in type 1 diabetes’ study-a national prospective cohort study of clinical and metabolic phenotyping of individuals with long-standing type 1 diabetes in the Netherlands

BMJ Open. 2024 Jun 19;14(6):e082453. doi: 10.1136/bmjopen-2023-082453. ABSTRACT PURPOSE: The ‘Biomarkers of heterogeneity in type 1 diabetes’ study cohort was set up to identify genetic, …

Paediatrics

Using mobile health to expedite access to specialty care for youth presenting to the emergency department with concussion at highest risk of developing persisting symptoms: a protocol paper for a non-randomised hybrid implementation-effectiveness trial

BMJ Open. 2024 Jun 19;14(6):e082644. doi: 10.1136/bmjopen-2023-082644. ABSTRACT INTRODUCTION: Paediatric concussion is a common injury. Approximately 30% of youth with concussion will experience persisting postconcussion …

Paediatrics

Screening for adverse social conditions in child healthcare settings: protocol for a systematic review

BMJ Open. 2024 Jun 19;14(6):e081958. doi: 10.1136/bmjopen-2023-081958. ABSTRACT INTRODUCTION: Adverse social conditions affect children’s development and health outcomes from preconception throughout their life course. Early …

Paediatrics

Exploring early DNA methylation alterations in type 1 diabetes: implications of glycemic control

Front Endocrinol (Lausanne). 2024 Jun 5;15:1416433. doi: 10.3389/fendo.2024.1416433. eCollection 2024. ABSTRACT BACKGROUND: Prolonged hyperglycemia causes diabetes-related micro- and macrovascular complications, which combined represent a significant …

Paediatrics

Application value of multi-gene mutation detection in the clinical management of pediatric papillary thyroid carcinoma: a preliminary exploration

Front Endocrinol (Lausanne). 2024 Jun 5;15:1405142. doi: 10.3389/fendo.2024.1405142. eCollection 2024. ABSTRACT OBJECTIVES: Thyroid cancer rarely occurs in children and adolescents. Molecular markers such as BRAF, …

Paediatrics

Exploring Splicing Modulation as an Innovative Approach to Combat Pancreatic Cancer: SF3B1 Emerges as a Prognostic Indicator and Therapeutic Target

Int J Biol Sci. 2024 Jun 3;20(8):3173-3184. doi: 10.7150/ijbs.92671. eCollection 2024. ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) poses significant challenges in terms of prognosis and treatment. …