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The prevalence of vertical transmission of human immunodeficiency virus and associated factors among exposed infants in Eastern Lake zone and Southern Highland of Tanzania: a cross-sectional study

HIV Res Clin Pract. 2024 Dec;25(1):2378575. doi: 10.1080/25787489.2024.2378575. Epub 2024 Jul 16. ABSTRACT BACKGROUND: Globally, the rate of antiretroviral therapy coverage for pregnant women living …

Optical genome mapping with genome sequencing identifies subtelomeric Xq28 deletion and inserted 7p22.3 duplication in a male with multisystem developmental disorder

Am J Med Genet A. 2024 Jul 16:e63814. doi: 10.1002/ajmg.a.63814. Online ahead of print. ABSTRACT We report a 17-year-old male with supravalvular stenosis, initial failure …

Estimating the Global and Regional Burden of Streptococcus pneumoniae Meningitis in Children: Protocol for a Systematic Review and Meta-Analysis

JMIR Res Protoc. 2024 Jul 16;13:e50678. doi: 10.2196/50678. ABSTRACT BACKGROUND: Streptococcus pneumoniae (Spn) has been a leading cause of bacterial meningitis in children. The most …

The impact of long-term (≥5 years) cholecystectomy on gut microbiota changes and its influence on colorectal cancer risk: based on 16S rDNA sequencing analysis

Eur J Gastroenterol Hepatol. 2024 Jul 15. doi: 10.1097/MEG.0000000000002827. Online ahead of print. ABSTRACT BACKGROUND: Colorectal cancer (CRC) continues to be a major global health …

Evaluating the Clinical Impact and Feasibility of Therapeutic Drug Monitoring of Pazopanib in a Real-World Soft-Tissue Sarcoma Cohort

Clin Pharmacokinet. 2024 Jul 16. doi: 10.1007/s40262-024-01399-8. Online ahead of print. ABSTRACT INTRODUCTION AND OBJECTIVE: Pazopanib is registered for metastatic renal cell carcinoma and soft-tissue …

Genetic and epigenetic instability as an underlying driver of progression and aggressive behavior in IDH-mutant astrocytoma

Acta Neuropathol. 2024 Jul 16;148(1):5. doi: 10.1007/s00401-024-02761-7. ABSTRACT In recent years, the classification of adult-type diffuse gliomas has undergone a revolution, wherein specific molecular features …