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Comparative efficacy of modified-live and inactivated vaccines in boosting responses to bovine respiratory syncytial virus, bovine parainfluenza virus Type 3, and bovine coronavirus following neonatal mucosal priming of beef calves

Can Vet J. 2024 Aug;65(8):791-801. ABSTRACT OBJECTIVE: This study compared clinical and immunological responses to coinfection challenge of beef calves mucosally primed and differentially boosted …

A national education program for rapid genomics in pediatric acute care: building workforce confidence, competence and capability

Genet Med. 2024 Jul 30:101224. doi: 10.1016/j.gim.2024.101224. Online ahead of print. ABSTRACT PURPOSE: To develop and evaluate a scalable national program to build confidence, competence …

Proton pump inhibitor effect on esophageal protein signature of eosinophilic esophagitis, prediction, and evaluation of treatment response

Allergy. 2024 Aug 2. doi: 10.1111/all.16261. Online ahead of print. ABSTRACT BACKGROUND: Recently, we have identified a dysregulated protein signature in the esophageal epithelium of …

Candesartan restores blood-brain barrier dysfunction, mitigates aberrant gene expression, and extends lifespan in a knockin mouse model of epileptogenesis

Clin Sci (Lond). 2024 Aug 2:CS20240771. doi: 10.1042/CS20240771. Online ahead of print. ABSTRACT Blockade of Angiotensin type 1 receptor (AT1R) has potential therapeutic utility in …

Impact of cancer on the mortality of patients with idiopathic inflammatory myopathies by flexible parametric multistate modelling

J Intern Med. 2024 Aug 2. doi: 10.1111/joim.20003. Online ahead of print. ABSTRACT BACKGROUND: Patients with idiopathic inflammatory myopathies (IIM) have an increased risk of …

Real-world data confirm elexacftor/tezacaftor/ivacaftor modulators halves sweat chloride concentration in eligible people with cystic fibrosis

APMIS. 2024 Aug 2. doi: 10.1111/apm.13453. Online ahead of print. ABSTRACT Sweat chloride concentration, a diagnostic feature in cystic fibrosis (CF), reflects CF transmembrane conductance …