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Paediatrics

Improving adherence to severe malaria treatment guidelines in children at a Ugandan regional hospital: assessment of a quality improvement initiative

Malar J. 2024 Aug 15;23(1):245. doi: 10.1186/s12936-024-05076-w. ABSTRACT BACKGROUND: Malaria is the leading cause of hospitalizations and death in Uganda, particularly in children under the …

Paediatrics

Functional cure induced by tenofovir alafenamide plus peginterferon-alpha-2b in young children with chronic hepatitis B: a case series study

BMC Infect Dis. 2024 Aug 15;24(1):830. doi: 10.1186/s12879-024-09723-0. ABSTRACT BACKGROUND AND AIMS: Data on the safety and effectiveness of tenofovir alafenamide (TAF) plus peginterferon-alpha (Peg-IFN-α) …

Paediatrics

Mecapegfilgrastim for prophylaxis of febrile neutropenia in children and adolescents with rhabdomyosarcoma or Ewing sarcoma: a prospective, single-arm, pilot study

BMC Cancer. 2024 Aug 15;24(1):1013. doi: 10.1186/s12885-024-12766-w. ABSTRACT BACKGROUND: The chemotherapy regimens recommended for both rhabdomyosarcoma (RMS) and Ewing sarcoma (ES) patients are myelosuppressive and …

Paediatrics

A radiomics nomogram based on multiparametric MRI for diagnosing focal cortical dysplasia and initially identifying laterality

BMC Med Imaging. 2024 Aug 15;24(1):216. doi: 10.1186/s12880-024-01374-6. ABSTRACT BACKGROUND: Focal cortical dysplasia (FCD) is the most common epileptogenic developmental malformation. The diagnosis of FCD …

Paediatrics

Unraveling neuroimaging insights in developmental epileptic encephalopathy type 25: a comprehensive review of reported cases and a novel SLC13A5 variant

Acta Neurol Belg. 2024 Aug 15. doi: 10.1007/s13760-024-02611-z. Online ahead of print. ABSTRACT Developmental and epileptic encephalopathy type 25 with amelogenesis imperfecta (DEE25) is a …

Child And Adolescent Mental Health

Childhood Trauma Questionnaire-based child maltreatment profiles to predict efficacy of the Cognitive Behavioral Analysis System of Psychotherapy versus non-specific psychotherapy in adults with early-onset chronic depression: cluster analysis of data from a randomised controlled trial

Lancet Psychiatry. 2024 Sep;11(9):709-719. doi: 10.1016/S2215-0366(24)00209-8. ABSTRACT BACKGROUND: Child maltreatment is a broadly confirmed risk factor for mental and physical illness. Some psychological treatments specifically …

Child And Adolescent Mental Health

Objective and subjective experiences of childhood maltreatment and their relationships with cognitive deficits: a cohort study in the USA

Lancet Psychiatry. 2024 Sep;11(9):720-730. doi: 10.1016/S2215-0366(24)00224-4. ABSTRACT BACKGROUND: Cognitive deficits might contribute to the elevated risk of life-course psychopathology observed in maltreated children. Leading theories …