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Paediatrics

Hsa_circ_0006010 and hsa_circ_0002903 in peripheral blood serve as novel diagnostic, surveillance and prognostic biomarkers for disease progression in chronic myeloid leukemia

BMC Cancer. 2024 Sep 20;24(1):1172. doi: 10.1186/s12885-024-12943-x. ABSTRACT BACKGROUND: In the era of tyrosine kinase inhibitor (TKI) treatment, the progression of chronic myeloid leukemia (CML) …

Paediatrics

An integrated machine learning model enhances delayed graft function prediction in pediatric renal transplantation from deceased donors

BMC Med. 2024 Sep 20;22(1):407. doi: 10.1186/s12916-024-03624-4. ABSTRACT BACKGROUND: Kidney transplantation is the optimal renal replacement therapy for children with end-stage renal disease; however, delayed …

Neonatal Medicine

Anorectal Malformations (ARM) and associated maternal factors among children at Tikur Anbessa Specialized Hospital and St. Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia: An unmatched case-control study

PLoS One. 2024 Sep 20;19(9):e0309298. doi: 10.1371/journal.pone.0309298. eCollection 2024. ABSTRACT INTRODUCTION: Anorectal malformations (ARMs) are birth defects that affect the rectum, anus, and surrounding structures. …

Paediatrics

Development of a signs and symptoms outcome measure for caregivers of patients with methylmalonic acidemia and propionic acidemia (MMAPAQ)

Mol Genet Metab. 2024 Sep 13;143(1-2):108577. doi: 10.1016/j.ymgme.2024.108577. Online ahead of print. ABSTRACT BACKGROUND AND OBJECTIVE: Methylmalonic acidemia (MMA) and propionic acidemia (PA) are rare …

Paediatrics

Generation of an infantile GM1 gangliosidosis induced pluripotent stem cell line (CHOCi005-A) for disease modeling and therapeutic testing

Stem Cell Res. 2024 Sep 7;81:103552. doi: 10.1016/j.scr.2024.103552. Online ahead of print. ABSTRACT GM1 gangliosidosis (GM1) is a rare autosomal recessive neurogenerative lysosomal storage disease …