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Efficacy of a Ready-to-Feed Starter Liquid Infant Formula Containing 2-Fucosyllactose and Lacto-N-Neotetraose in Chinese Infants: Protocol for a Double Blind, Randomized Controlled Trial

JMIR Res Protoc. 2025 Oct 31;14:e66489. doi: 10.2196/66489. ABSTRACT BACKGROUND: Bioactive compounds, such as human milk oligosaccharides (HMOs), impact the development of the intestinal microbiome …

Risk and response adapted treatment in pediatric Epstein-Barr virus associated hemophagocytic lymphohistiocytosis

J Infect Dis. 2025 Oct 31:jiaf556. doi: 10.1093/infdis/jiaf556. Online ahead of print. ABSTRACT BACKGROUND: Hemophagocytic lymphohistiocytosis (HLH) is a rapidly progressive and often fatal disorder …

Treatment with Minicircle DNA Expressing a FGF23 Fragment in a Clinically relevant Mouse Model of X-Linked Hypophosphatemic Rickets

Adv Sci (Weinh). 2025 Oct 31:e08870. doi: 10.1002/advs.202508870. Online ahead of print. ABSTRACT X-linked hypophosphatemic rickets (XLHR) is a rare X-linked dominant skeletal dysplasia caused …

Brief Digital Interventions for Psychological Distress: An AI-Enhanced Response-Adaptive Randomized Clinical Trial

JAMA Netw Open. 2025 Oct 1;8(10):e2540502. doi: 10.1001/jamanetworkopen.2025.40502. ABSTRACT IMPORTANCE: A large proportion of college students report experiencing psychological distress. Smartphone app-based interventions may alleviate …

Clinical Trials of Fetal Therapy With Continuing Neonatal Interventions: Legal Requirements and Customary Procedures Regarding Parental Consent. The BOOSTB4 Trial as a Case Study

Prenat Diagn. 2025 Oct 31. doi: 10.1002/pd.70012. Online ahead of print. ABSTRACT OBJECTIVE: To analyze the legal consent requirements and customary procedures in clinical trials …