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Dried Blood Spots Sampling and Population Pharmacokinetic Modeling for Dosing Optimization of Piperacillin in Chinese Neonates

J Clin Pharmacol. 2024 Oct 7. doi: 10.1002/jcph.6145. Online ahead of print. ABSTRACT Piperacillin is commonly used off-label in neonates for the treatment of bacterial …

Apneic uptake of atmospheric O2 by deeply hypothermic nestlings of the white-footed mouse (Peromyscus leucopus): circulation and lungs

J Comp Physiol B. 2024 Oct 8. doi: 10.1007/s00360-024-01585-x. Online ahead of print. ABSTRACT Nestling white-footed mice (Peromyscus leucopus) are born in the earliest days …

-New frontiers in domain-inspired radiomics and radiogenomics: increasing role of molecular diagnostics in CNS tumor classification and grading following WHO CNS-5 updates

Cancer Imaging. 2024 Oct 7;24(1):133. doi: 10.1186/s40644-024-00769-6. ABSTRACT Gliomas and Glioblastomas represent a significant portion of central nervous system (CNS) tumors associated with high mortality …

In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma

Genome Biol. 2024 Oct 7;25(1):256. doi: 10.1186/s13059-024-03404-6. ABSTRACT BACKGROUND: Genetic perturbation screens with single-cell readouts have enabled rich phenotyping of gene function and regulatory networks. …