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Cryptosporidium PI(4)K inhibitor EDI048 is a gut-restricted parasiticidal agent to treat paediatric enteric cryptosporidiosis

Nat Microbiol. 2024 Oct 8. doi: 10.1038/s41564-024-01810-x. Online ahead of print. ABSTRACT Diarrhoeal disease caused by Cryptosporidium is a major cause of morbidity and mortality …

Neurodevelopmental outcomes among children with congenital gastrointestinal anomalies using Korean National Health Insurance claims data

Sci Rep. 2024 Oct 8;14(1):23442. doi: 10.1038/s41598-024-74515-0. ABSTRACT This study investigated neurodevelopment and risk factors in children surgically treated for congenital gastrointestinal anomalies (CGIA), excluding …

Early-onset preeclampsia/gestational hypertension may be associated with a low incidence of cerebral palsy at 3 years old in singleton very low-birth-weight infants born at 28-31 weeks of gestation (EOPE-DQ study): a multi-center retrospective cohort study in 2013-2016

Hypertens Res. 2024 Oct 8. doi: 10.1038/s41440-024-01929-8. Online ahead of print. ABSTRACT Our aim was to evaluate the effects of any types of hypertensive disorders …

Human pancreatic islet-derived stromal cells reveal combined features of mesenchymal stromal cells and pancreatic stellate cells

Stem Cell Res Ther. 2024 Oct 8;15(1):351. doi: 10.1186/s13287-024-03963-2. ABSTRACT BACKGROUND: Mesenchymal stromal cells (MSCs) are recognized for their potential in regenerative medicine, attributed to …

Process mapping with failure mode and effects analysis to identify determinants of implementation in healthcare settings: a guide

Implement Sci Commun. 2024 Oct 8;5(1):110. doi: 10.1186/s43058-024-00642-4. ABSTRACT BACKGROUND: Generating and analyzing process maps can help identify and prioritize barriers to the implementation of …

Comprehensive analysis of NGS-based expanded carrier screening and follow-up in southern and southwestern China: results from 3024 Chinese individuals

Hum Genomics. 2024 Oct 8;18(1):111. doi: 10.1186/s40246-024-00680-y. ABSTRACT BACKGROUND: This study aimed to screen southern and southwestern Chinese individuals using expanded carrier screening (ECS), which …