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Development of a cycling protocol for the in vitro assessment of enamel erosion and the effect of a fluoridated mouthrinse containing micrometric- and nano-sized trimetaphosphate on erosion prevention

Clin Oral Investig. 2025 Dec 6;29(12):607. doi: 10.1007/s00784-025-06644-3. ABSTRACT OBJECTIVES: To develop a cycling protocol for the evaluation of enamel erosion and to evaluate the …

Development of a YOLOv8-based deep learning model for detecting and segmenting dental restorations and dental applications in panoramic radiographs of mixed dentition

Br Dent J. 2025 Dec 5. doi: 10.1038/s41415-025-9009-4. Online ahead of print. ABSTRACT Background The objective of this study was to develop a deep learning …

Effectiveness of a Remote Intervention Program for Self-Management Behaviors in Adolescents and Young Adults With Inflammatory Bowel Disease Based on the Self-Determination Theory: Randomized Controlled Trial Across 2 Centers

J Med Internet Res. 2025 Dec 5;27:e79370. doi: 10.2196/79370. ABSTRACT BACKGROUND: The prevalence of inflammatory bowel disease (IBD) has been on the rise, with adolescents …

Using Generative AI to Co-Design Digital Mental Health Interventions With Adolescents in Rural South Africa: Qualitative Thematic Analysis of Participatory Workshops

J Med Internet Res. 2025 Dec 5;27:e73535. doi: 10.2196/73535. ABSTRACT BACKGROUND: Digital mental health interventions (DMHIs) offer a scalable approach to address adolescent depression and …

Digital Training for Mental Health Promotion in Young People With Climate Change-Related Distress: Protocol for a Feasibility Randomized Controlled Trial

JMIR Res Protoc. 2025 Dec 5;14:e77764. doi: 10.2196/77764. ABSTRACT BACKGROUND: Efforts in mental health research have long focused on the care and long-term outcomes of …

Depression and anxiety mediate the relationship between COVID-19 stay-at-home orders and tobacco and marijuana use

PLoS One. 2025 Dec 5;20(12):e0337996. doi: 10.1371/journal.pone.0337996. eCollection 2025. ABSTRACT BACKGROUND: The COVID-19 pandemic had notable impacts on the mental health of the U.S. population. …

Patterns of substance use in people with severe mental illness: A case-control study in Ethiopia

PLoS One. 2025 Dec 5;20(12):e0332107. doi: 10.1371/journal.pone.0332107. eCollection 2025. ABSTRACT BACKGROUND: Substance use disorders are increasingly prevalent in sub-Saharan African countries, with evident bidirectional risk …

Benefits of psychosocial support for adolescent mothers on infant development and maternal mental wellbeing in Rakai and Kyotera, Uganda: Quasi-experimental study

PLoS One. 2025 Dec 5;20(12):e0325463. doi: 10.1371/journal.pone.0325463. eCollection 2025. ABSTRACT Twenty-four percent of Ugandan women give birth before the age of twenty, which is the …