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Overexpression of Nfs1 Cysteine Desulphurase Relieves Sevoflurane-Induced Neurotoxicity and Cognitive Dysfunction in Neonatal Mice Via Suppressing Oxidative Stress and Ferroptosis

J Biochem Mol Toxicol. 2024 Nov;38(11):e70051. doi: 10.1002/jbt.70051. ABSTRACT Clinical evidence suggests that multiple exposures to sevoflurane in young people may be detrimental to cognitive …

Epigenetic Activation of the CMTM6-IGF2BP1-EP300 Positive Feedback Loop Drives Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma

Adv Sci (Weinh). 2024 Nov 3:e2406714. doi: 10.1002/advs.202406714. Online ahead of print. ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant tumor with a dismal …

AAAAI Position Statement on Changing Electronic Health Record Allergy Documentation to “Alerts” to Lead to Easily Understood, Actionable Labels

J Allergy Clin Immunol Pract. 2024 Nov 2:S2213-2198(24)01051-1. doi: 10.1016/j.jaip.2024.09.034. Online ahead of print. ABSTRACT The term “allergy” is inaccurate for the vast majority of …

An International Delphi Consensus on the Management of Pollen-Food-Allergy Syndrome: A Work Group Report of the AAAAI Adverse Reactions to Foods Committee

J Allergy Clin Immunol Pract. 2024 Nov 2:S2213-2198(24)01069-9. doi: 10.1016/j.jaip.2024.09.037. Online ahead of print. ABSTRACT BACKGROUND: Pollen-food-allergy syndrome (PFAS) is common among patients with allergic …

Diagnostic accuracy of the point-of-care standard G6PD test™ (SD Biosensor) for glucose-6-phosphate dehydrogenase deficiency: a systematic review and meta-analysis

Malar J. 2024 Nov 2;23(1):327. doi: 10.1186/s12936-024-05144-1. ABSTRACT BACKGROUND: Glucose-6-Phosphate Dehydrogenase deficiency (G6PDd) is a common genetic enzymopathy that can induce haemolysis triggered by various …

Estimating at-risk couple rates across 1000 exome sequencing data cohort for 176 genes and its importance relevance for health policies

Eur J Hum Genet. 2024 Nov 2. doi: 10.1038/s41431-024-01726-4. Online ahead of print. ABSTRACT The development of high-throughput technologies has enabled Expanded Carrier screening (ECS) …