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Redistribution of PU.1 partner transcription factor RUNX1 binding secures cell survival during leukemogenesis

EMBO J. 2024 Nov 14. doi: 10.1038/s44318-024-00295-y. Online ahead of print. ABSTRACT Transcription factors (TFs) orchestrating lineage-development often control genes required for cellular survival. However, …

Accounting for heterogeneity due to environmental sources in meta-analysis of genome-wide association studies

Commun Biol. 2024 Nov 14;7(1):1512. doi: 10.1038/s42003-024-07236-9. ABSTRACT Meta-analysis of genome-wide association studies (GWAS) across diverse populations offers power gains to identify loci associated with …

The role of co-occurring conditions and genetics in the associations of eating disorders with attention-deficit/hyperactivity disorder and autism spectrum disorder

Mol Psychiatry. 2024 Nov 14. doi: 10.1038/s41380-024-02825-w. Online ahead of print. ABSTRACT Eating disorders (EDs) commonly co-occur with other psychiatric and neurodevelopmental disorders including attention-deficit/hyperactivity …

Longitudinal analyses of infants’ microbiome and metabolome reveal microbes and metabolites with seemingly coordinated dynamics

Commun Biol. 2024 Nov 14;7(1):1506. doi: 10.1038/s42003-024-07015-6. ABSTRACT Population studies have shown that the infant’s microbiome and metabolome undergo significant changes in early childhood. However, …

“Instead of Building More Buildings, They Should Plant More Trees”, a Photovoice Study of Determinants of Happiness and Sadness Among East London Adolescents

Qual Health Res. 2024 Nov 14:10497323241291667. doi: 10.1177/10497323241291667. Online ahead of print. ABSTRACT Globally, mental health problems in adolescents, alongside associated morbidity and mortality, have …

Parental mental disorders and ages of onset of severe mental disorders in offspring: A nationwide family-link study

J Psychiatr Res. 2024 Nov 9;180:443-450. doi: 10.1016/j.jpsychires.2024.11.018. Online ahead of print. ABSTRACT OBJECTIVE: The current study used a retrospective study design to investigate the …